Comparison

NQO1 Antibody (Center)

Item no. ABC-AP7350C-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Immunofluorescence, Western Blot, Flow cytometry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Available
Primary Accession
P15559
Antigen Type
Synthetic Peptide
Bio Background
NQO1 is a member of the NAD(P)H dehydrogenase(quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
Bio References
Hubackova, M., Vaclavikova, R. Pharmacogenet. Genomics 19 (7), 505-512 (2009) Canova, C., Hashibe, M. Cancer Res. 69 (7), 2956-2965 (2009) Li, Y. and Jaiswal, A.K. J. Biol. Chem. 267 (21), 15097-15104 (1992)
Gene ID
1728
Gene Name
NQO1
Reactivity
H
Calculated MW
30868
Antigen Region
118-144
Antigen Source
HUMAN
Target/Specificity
This NQO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NQO1.
NCBI Accession
NP_000894.1; NP_001020604.1; NP_001020605.1

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