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MLH1 Antibody (C-term)

MLH1 Antibody (C-term)

Item no.	ABC-AP7464b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1
Available
Primary Accession	P40692
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). The protein is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
Bio References	Bronner C.E., Baker S.Nature 368:258-261(1994) Kolodner R.D., Hall N.Cancer Res. 55:242-248(1995) Han H.-J., Maruyama M.Hum. Mol. Genet. 4:237-242(1995) Bellacosa A.Proc. Natl. Acad. Sci. U.S.A. 96:3969-3974(1999)
Clonality	Polyclonal
Clone/Animal Names	RB18204
Gene ID	4292
Gene Name	MLH1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-MLH1 Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 85 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Isotype	Rabbit Ig
Calculated MW	84601
Antigen Source	HUMAN
Target/Specificity	This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human MLH1.
NCBI Accession	NP_000240.1; NP_001161089.1; NP_001161090.1; NP_001161091.1; NP_001245200.1; NP_001245202.1; NP_001245203.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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