Comparison

GIPR Antibody (N-term)

Item no. ABC-AP7495A
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, FC, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products GIPR, Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor
Available
Primary Accession
P48546
Antigen Type
Synthetic Peptide
Application
WB, FC, IHC-P
Bio Background
GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
Bio References
Herbach, N. Am. J. Physiol. Renal Physiol. 296 (4), F819-F829 (2009) Rudovich, N., Kaiser, S. Regul. Pept. 142 (3), 138-145 (2007) Nitz, I., Fisher, E. Mol Nutr Food Res 51 (8), 1046-1052 (2007)
Clonality
Polyclonal
Clone/Animal Names
RB18125
Gene ID
2696
Gene Name
GIPR
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of GIPR antibody (N-term) (Cat.#AP7495a) in HL60 cell line lysates (35ug/lane). GIPR (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
GIPR Antibody (N-term) (Cat. #AP7495A)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GIPR Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Legend image 3
GIPR Antibody (Center) (Cat. #AP7495a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Isotype
Rabbit Ig
Calculated MW
53157
Antigen Region
7-38
Antigen Source
HUMAN
Target/Specificity
This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.
NCBI Accession
NP_000155.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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