ERBB4 Antibody(C-term)

Synthetic Peptide

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Polyclonal

2066

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of anti-ErbB4 Pab (Cat. #AP7631b) in T-47D cell lysate. ErbB4 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

1:1000

IHC-P

Rabbit Ig

1276-1308

This ERBB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1276-1308 amino acids from the C-terminal region of human ERBB4.