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FGFR1 Antibody (Y463)

FGFR1 Antibody (Y463)

Item no.	ABC-AP7636D-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Sarcoma Cell Biology Cell Culture Cytokines Western Blot Primary Antibodies Astrocytoma Bladder Cancer Colorectal Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Fibroblast growth factor receptor 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Available
Primary Accession	P11362
Other Accession	Q04589; P16092; P21804
Antigen Type	Synthetic Peptide
Bio Background	FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
Bio References	Jiao, J., et al., Arch. Biochem. Biophys. 410(2):187-200 (2003). Fu, L., et al., J. Comp. Neurol. 462(2):265-273 (2003). Lundin, L., et al., Exp. Cell Res. 287(1):190-198 (2003). Kiselyov, V.V., et al., Structure (Camb.) 11(6):691-701 (2003). Baumann, H., et al., J. Biol. Chem. 278(18):16198-16208 (2003).
Gene ID	2260
Gene Name	FGFR1
Reactivity	H
Predicted	C, M, Rat
Calculated MW	91868
Antigen Region	441-470
Antigen Source	HUMAN
Target/Specificity	This FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from human FGFR1.
NCBI Accession	NP_001167534.1; NP_001167535.1; NP_001167536.1; NP_001167537.1; NP_001167538.1; NP_056934.2; NP_075593.1; NP_075594.1; NP_075598.2

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Amount: 80 ul

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