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MEK3 (MAP2K3) Antibody (N-term)

MEK3 (MAP2K3) Antibody (N-term)

Item no.	ABC-AP7915a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Senescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Yustein, J.T., et al., Oncogene 22(40):6129-6141 (2003). Edlund, S., et al., Mol. Biol. Cell 14(2):529-544 (2003). Lim, S., et al., J. Biol. Chem. 277(28):25040-25046 (2002). Han, Q., et al., J. Biol. Chem. 277(50):48379-48385 (2002). Wang, W., et al., Mol. Cell. Biol. 22(10):3389-3403 (2002).
NCBI	NP_002747.2,NP_659731.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity mitogen-activated protein kinase kinase 3,MAP kinase kinase 3,MAPKK 3,MAPK/ERK kinase 3,MEK 3,Stress-activated protein kinase kinase 2,SAPK kinase 2,SAPKK-2,SAPKK2,MAP2K3,MEK3,MKK3,PRKMK3,SKK2
Similar products	MAP2K3, MKK3, Dual specificity mitogen-activated protein kinase kinase 3, MAPK/ERK kinase 3, MEK3, PRKMK3, MAP kinase kinase 3, MAPKK 3, MEK 3, Stress-activated protein kinase kinase 2, SAPK kinase 2, SAPKK-2, SAPKK2, SKK2
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Immunology; Signal Transduction; Amyotrophic Lateral Sclerosis (ALS); Anti-Kinome Antibodies; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling; Apoptosis signaling
Manufacturer - Targets	This MEK3 (MAP2K3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human MEK3 (MAP2K3).
Bio Background	MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB0928
Gene Name	MAP2K3
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	39318
Antigen Source	HUMAN
Antigen Region	15-45
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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