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PLK1 Antibody (C-term)

PLK1 Antibody (C-term)

Item no.	ABC-AP7937a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PLK1, Serine/threonine-protein kinase 13, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, STPK13, PLK-1
Available
Primary Accession	P53350
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Bio References	Ree, A.H., et al., Oncogene 22(55):8952-8955 (2003). Cheng, K.Y., et al., EMBO J. 22(21):5757-5768 (2003). Elia, A.E., et al., Cell 115(1):83-95 (2003). Lin, H.R., et al., J. Biol. Chem. 278(38):35979-35987 (2003). Neef, R., et al., J. Cell Biol. 162(5):863-875 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB00878
Gene ID	5347
Gene Name	PLK1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-PLK Pab (Cat. #AP7937a) in A375 cell lysate. PLK (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q07832
Predicted	M
Isotype	Rabbit Ig
Calculated MW	68255
Antigen Region	573-603
Antigen Source	HUMAN
Target/Specificity	This PLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-603 amino acids from the C-terminal region of human PLK1.
NCBI Accession	NP_005021.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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