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BRD4 Antibody (C-term)

BRD4 Antibody (C-term)

Item no.	ABC-AP8051b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BRD4, HUNK1, Bromodomain-containing protein 4, Protein HUNK1
Available
Primary Accession	O60885
Antigen Type	Synthetic Peptide
Application	IHC-P
Bio Background	BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t(15; 19)(q13; p13.1), which defines an upper respiratory tract carcinoma in young people.
Bio References	Maruyama, T., et al., Mol. Cell. Biol. 22(18):6509-6520 (2002). French, C.A., et al., Am. J. Pathol. 159(6):1987-1992 (2001). Dey, A., et al., Mol. Cell. Biol. 20(17):6537-6549 (2000).
Clonality	Polyclonal
Clone/Animal Names	RB3422
Gene ID	23476
Gene Name	BRD4
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 1	IHC-P
Dilution image 1	1:50~100
Legend image 2	Subnuclear distribution of cellular proteins. CHOBgl40 cells grown on coverslips were either directly or after treatment with 0.5% Triton X-100, incubated with antibodies against Brd4 (images 4 and 5). PI, propidium iodide staining of cellular DNA (images 6).WC, whole cells.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	Q9ESU6
Predicted	M
Isotype	Rabbit Ig
Calculated MW	152219
Antigen Region	1313-1342
Antigen Source	HUMAN
Target/Specificity	This BRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1313~1342 amino acids from the C-terminal region of human BRD4.
NCBI Accession	NP_055114.1; NP_490597.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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