Comparison

Fructose 6 Phosphate Kinase Antibody (N-term)

Item no. ABC-AP8137a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255|HAMAP-Rule:MF_03184}, ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}, PFK-M, 27111 {ECO:0000255|HAMAP-Rule:MF_03184}, 6-phosphofructokinase type A, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphohe
Available
Primary Accession
P08237
Antigen Type
Synthetic Peptide
Bio Background
Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1, 6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.
Bio References
Howard, T.D., et al., Genomics 34(1):122-127 (1996).
Vasconcelos, O., et al., Proc. Natl. Acad. Sci. U.S.A. 92(22):10322-10326 (1995).
Raben, N., et al., J. Biol. Chem. 268(7):4963-4967 (1993).
Yamasaki, T., et al., Gene 104(2):277-282 (1991).
Sharma, P.M., et al., J. Biol. Chem. 265(16):9006-9010 (1990).
Gene ID
5213
Gene Name
PFKM
Reactivity
H
Calculated MW
85183
Antigen Region
122-151
Antigen Source
HUMAN
Target/Specificity
This Fructose 6 Phosphate Kinase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the N-terminal region of human Fructose 6 Phosphate Kinase.
NCBI Accession
NP_000280.1; NP_001160158.1; NP_001160159.1; NP_001160160.1

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