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GCKR Antibody (N-term)

GCKR Antibody (N-term)

Item no.	ABC-AP8143a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Veiga-da-Cunha, M., et al., Diabetologia 46(5):704-711 (2003). Hayward, B.E., et al., Genomics 49(1):137-142 (1998). Hayward, B.E., et al., Mamm. Genome 7(6):454-458 (1996). Warner, J.P., et al., Mamm. Genome 6(8):532-536 (1995). Vaxillaire, M., et al., Diabetes 43(3):389-395 (1994).
NCBI	NP_001477.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Glucokinase regulatory protein,GKRP,Glucokinase regulator,GCKR
Similar products	GCKR, Glucokinase regulatory protein, GKRP, Glucokinase regulator
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction
Manufacturer - Targets	This GCKR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GCKR.
Bio Background	GCKR belongs to the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. The GCKR gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB3929
Gene Name	GCKR {ECO:0000303\|PubMed:8589523, ECO:0000312\|HGNC:HGNC:4196}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	68685
Antigen Source	HUMAN
Antigen Region	1-30
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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