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BCL2L11 Antibody (Center)

BCL2L11 Antibody (Center)

Item no.	ABC-AP8553c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL2L11, BIM, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, Bcl2-L-11
Available
Primary Accession	O43521
Antigen Type	Synthetic Peptide
Application	IHC-P, FC, WB
Bio Background	BCL2L11 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.
Bio References	Hippe, D., et.al., J. Cell. Sci. 122 (PT 19), 3511-3521 (2009) Putcha, G.V., et.al., Neuron 38 (6), 899-914 (2003)
Clonality	Polyclonal
Clone/Animal Names	RB22105
Gene ID	10018
Gene Name	BCL2L11
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of BCL2L11 Antibody (Center) (Cat. #AP8553c) in K562, HL-60 cell line lysates (35ug/lane). BCL2L11 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human colon carcinoma reacted with BCL2L11 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	Immunohistochemical analysis of paraffin-embedded H. kidney section using BCL2L11 Antibody (Center)(Cat#AP8553c). AP8553c was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Type image 3	IHC-P
Dilution image 3	1:25
Legend image 4	Flow cytometric analysis of WiDr cells using BCL2L11 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	O88498; O54918
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	22171
Antigen Region	134-160
Antigen Source	HUMAN
Target/Specificity	This BCL2L11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-160 amino acids from the Central region of human BCL2L11.
NCBI Accession	NP_001191035.1; NP_001191036.1; NP_001191037.1; NP_001191038.1; NP_001191039.1; NP_001191040.1; NP_001191041.1; NP_001191042.1; NP_006529.1; NP_619527.1; NP_619528.1; NP_619529.1; NP_619530.1; NP_619531.1; NP_61953

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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