FLCN Antibody (C-term)

Item no.	ABC-AP8658b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Khoo,S.K., et.al., J. Med. Genet. 39 (12), 906-912 (2002) Shin,J.H., et.al., J. Med. Genet. 40 (5), 364-367 (2003)
NCBI	NP_653207.1,NP_659434.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Folliculin,BHD skin lesion fibrofolliculoma protein,Birt-Hogg-Dube syndrome protein,FLCN,BHD
Similar products	Folliculin, FLCN, BHD, BHD skin lesion fibrofolliculoma protein, Birt-Hogg-Dube syndrome protein
Available
Manufacturer - Category	Primary Antibodies; Cancer
Manufacturer - Targets	This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human FLCN.
Bio Background	FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB20960
Gene Name	FLCN {ECO:0000303\|PubMed:15657874, ECO:0000312\|HGNC:HGNC:27310}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, M, Rat
Calculated Molecular Weight	64473
Antigen Source	HUMAN
Antigen Region	505-534
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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