RGS4 Antibody (Center)

Synthetic Peptide

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

Polyclonal

5999

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of RGS4 Antibody (Center) (Cat. #AP8879c) in MDA-MB231 cell line lysates (35ug/lane). RGS4 (arrow) was detected using the purified Pab.

1:1000

WB

Western blot analysis of RGS4 (arrow) using rabbit polyclonal RGS4 Antibody (Center) (Cat. #AP8879c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RGS4 gene.

1:1000

B, Pr, Rb, Rat

23256

HUMAN

NP_001095915.1; NP_001106851.1; NP_001106852.1; NP_005604.1