Comparison

SFRP1 Antibody (N-term)

Item no. ABC-AP9037A
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB, FC, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products sFRP-1, SFRP1, FRP1, FRP, FRP-1, SARP2, SARP-2, Secreted frizzled-related protein 1, Secreted apoptosis-related protein 2
Available
Primary Accession
Q8N474
Antigen Type
Synthetic Peptide
Application
FC, IHC-P, WB
Bio Background
SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer.
Bio References
Huang, D., et.al., J. Cancer Res. Clin. Oncol. 136 (3), 395-401 (2010);
Yang, Z.Q., et.al., Int. J. Cancer 125 (7), 1613-1621 (2009).
Clonality
Polyclonal
Clone/Animal Names
RB21557
Gene ID
6422
Gene Name
SFRP1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of SFRP1 Antibody (N-term) (Cat. #AP9037a) in K562 cell line lysates (35ug/lane). SFRP1 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human testis tissue reacted with SFRP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Legend image 3
SFRP1 Antibody (N-term) (Cat. #AP9037a) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Isotype
Rabbit Ig
Calculated MW
35386
Antigen Region
26-55
Antigen Source
HUMAN
Target/Specificity
This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.
NCBI Accession
NP_003003.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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