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ADRA1B Antibody (Center)

ADRA1B Antibody (Center)

Item no.	ABC-AP9404c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Metabolism Antibodies Obesity Immunohistochemistry Western Blot Cardiovascular Research Hypertension Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Alpha-1B adrenergic receptor, Alpha-1B adrenoreceptor, Alpha-1B adrenoceptor, ADRA1B
Available
Primary Accession	P35368
Other Accession	P15823; P97717; P43140; O02824; P97718; P35348; P18130
Antigen Type	Synthetic Peptide
Bio Background	Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Bio References	Mathias, R.A., J. Allergy Clin. Immunol. 125 (2), 336-346 (2010) Jensen, B.C., Circ Heart Fail 2 (6), 654-663 (2009) Gratacos, M., Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Gene ID	147
Gene Name	ADRA1B
Reactivity	H
Predicted	B, M, Rb, Rat
Calculated MW	56836
Antigen Region	270-297
Antigen Source	HUMAN
Target/Specificity	This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B.
NCBI Accession	NP_000670.1

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Amount: 80 ul

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