CD1E Antibody (Center)

Synthetic Peptide

CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.

Polyclonal

913

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of CD1E Antibody (Center)(Cat#AP9942c) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

CD1E Antibody (Center) (Cat. #AP9942c) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CD1E Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

1:50~100

FC

NP_112155.2

43626

HUMAN

NP_001036048.1; NP_001036049.1; NP_001036050.1; NP_001036051.1; NP_001036052.1; NP_001172036.1; NP_001172037.1; NP_001172039.1; NP_001172041.1; NP_001172042.1; NP_001172043.1; NP_001172044.1; NP_112155.2