Comparison

Bim Antibody

Item no. ABC-ASC10046
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998; 17:384-395.
Hsu SY, Lin P, and Hsueh AJ BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endocrinol. 1998; 12:1432-40.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Bim Antibody: BAM,BIM,BOD,Bcl-2-like protein 11,Bcl2-interacting mediator of cell death,Bcl2-L-11,BCL2-like 11 (apoptosis facilitator)
Similar products BIM, Bcl-2-like protein 11, Bcl2-interacting mediator of cell death, BOD, Bcl2-L-11, Bim Antibody: BAM, BCL2-like 11 (apoptosis facilitator)
Available
Manufacturer - Applications
Bim antibody can be used for detection of Bim by Western blot at 1 µg/mL. A 23 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 20 µg/mL.
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Immunology; Metabolism; Neuroscience; Signal Transduction; Apoptosis signaling; Mitochondrion
Manufacturer - Targets
BCL2L11;
Storage Conditions
Bim antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background
Bim Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat. Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Clonality
Polyclonal
Gene Name
BCL2L11
Reactivity
H, M, Rat
Calculated Molecular Weight
22171
Antigen Source
Homo sapiens
Purification
Bim Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
Bim antibody can be used for detection of Bim by Western blot at 1 µg/mL. A 23 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 20 µg/mL.
Positive Control
K562 Cell Lysate
Buffer
Bim Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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