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TL1A Antibody

TL1A Antibody

Item no.	ABC-ASC10187
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Chinnayan AM, O’Rourke K, Yu GL, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274:990-2. Kitson J, Raven T, Jiang YP, et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996; 384:372-5. Screaton GR, Xu XN, Olsen AL, et al. LARD: a new lymphoid-specific death domain containing receptor regulated by pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 1997; 94:4615-9. Bodmer JL, Burns K, Schneider P. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95). Immunity 1997; 6:79-88.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TL1A Antibody: TL1,TL1A,VEGI,VEGI192A,TL1,Tumor necrosis factor ligand superfamily member 15,TNF ligand-related molecule 1,tumor necrosis factor (ligand) superfamily,member 15
Similar products	TL1A, TL1, VEGI, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, tumor necrosis factor (ligand) superfamily, member 15, VEGI192A, TL1A Antibody: TL1
Available
Manufacturer - Category	Primary Antibodies; Cardiovascular; Immunology; Signal Transduction; Cytokine
Manufacturer - Targets	TNFSF15; This polyclonal antibody will not cross-react with TL1.
Storage Conditions	TL1A antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-?B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI).
Clonality	Polyclonal
Gene Name	TNFSF15
Reactivity	H, M, Rat
Calculated Molecular Weight	28087
Antigen Source	Homo sapiens
Purification	TL1A Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	TL1A antibody can be used for detection of TL1A by Western blot at 0.5 to 2 µg/mL.
Positive Control	PC-3 Cell Lysate
Buffer	TL1A Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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