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Bcl-xL Antibody

Bcl-xL Antibody

Item no.	ABC-ASC10251
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Primary
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lockshin RA, Osborne B, and Zakeri Z. Cell death in the third millennium. Cell Death Differ. 2000; 7:2-7. Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22:8590-607. Heiser D, Labi V, Erlacher M, et al. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp. Geron. 2004; 39:1125-35. Gonzalez-Garcia M, Perez-Ballestro R, Ding L et al. bcl-xL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 1994; 120:3033-42.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bcl-xL Antibody: BCLX,BCL2L,BCLXL,BCLXS,Bcl-X,bcl-xL,bcl-xS,PPP1R52,BCL-XL/S,BCLX,Bcl-2-like protein 1,Apoptosis regulator Bcl-X,Bcl2-L-1,BCL2-like 1
Similar products	Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCLX, bcl-xS, BCL-XL/S, BCL2L, Bcl-X, bcl-xL, BCLXL, BCLXS, PPP1R52, Bcl-xL Antibody: BCLX, BCL2-like 1
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Metabolism; Signal Transduction; Inflammasome; Jak-STAT signaling KEGG; Apoptosis; Apoptosis signaling; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	BCL2L1;
Storage Conditions	Bcl-xL antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	Bcl-xL Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.
Clonality	Polyclonal
Gene Name	BCL2L1
Reactivity	H
Calculated Molecular Weight	26049
Antigen Source	Homo sapiens
Purification	Bcl-xL Antibody is Bcl-xL is supplied as ion exchange chromatography purified IgG.ide.
Antibody Form	Liquid
Application Notes	Bcl-xL antibody can be used for detection of Bcl-xL by Western blot at 1 to 2 µg/mL.
Positive Control	A549 Cell Lysate
Buffer	Bcl-xL Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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