Comparison

SCARA5 Antibody

Item no. ABC-ASC10941
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, IF, ICC, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Primary Accession
Q6ZMJ2
Application
WB, IF, ICC, E
Bio Background
SCARA5 Antibody: Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains the collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery.
Bio References
Greaves DR, Gough PJ, and Gordon S. Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence. Curr. Op. Lipid. 1998; 9:425-32.
Jiang Y, Oliver P, Davies KE, et al. Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells. J. Biol. Chem. 2006; 281:11834-45.
Li JY, Paragas N, Ned RM, et al. Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev. Cell 2009; 16:35-46.
Clonality
Polyclonal
Gene ID
286133
Gene Name
SCARA5 {ECO:0000255|HAMAP-Rule:MF_03070}
Reactivity
H, M
Legend image 1
Western blot analysis of SCARA5 in human liver tissue lysate with SCARA5 antibody at 1 µg/mL.
Type image 1
WB
Legend image 2
Immunocytochemistry of SCARA5 in HepG2 cells with SCARA5 antibody at 2.5 µg/mL.
Type image 2
ICC
Legend image 3
Immunofluorescence of SCARA5 in HepG2 cells with SCARA5 antibody at 20 µg/mL.
Type image 3
IF
Other Accession
NP_776194; 47271477
Isotype
IgG
Calculated MW
53994
Antigen Source
Homo sapiens
Target/Specificity
SCARA5; At least four isoforms of SCARA5 are known to exist; this antibody will detect all four isoforms.
Purification
SCARA5 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
SCARA5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form
Liquid
Application Notes
SCARA5 antibody can be used for detection of SCARA5 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control
Human Spleen Tissue Lysate;
Buffer
SCARA5 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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