AGTR2 Antibody

AGTR2;

AGTR2 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

AGTR2 {ECO:0000303|PubMed:7790004, ECO:0000312|HGNC:HGNC:338}

41184

AGTR2 Antibody is affinity chromatography purified via peptide column.

AGTR2 antibody can be used for detection of AGTR2 by Western blot at 0.5 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.

AGTR2 Antibody is supplied in PBS containing 0.02% sodium azide.