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TYW3 Antibody

TYW3 Antibody

Item no.	ABC-ASC11335
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	Q6IPR3
Application	WB, E
Bio Background	TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Bio References	Noma A and Suzuki T. Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp. Ser. (Oxf) 2006; 65-6. Noma A, Kirino Y, Ikeuchi Y, et al. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J. 2006; 25:2142-54
Clonality	Polyclonal
Gene ID	127253
Gene Name	TYW3
Reactivity	H, M
Legend image 1	Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Type image 1	WB
Other Accession	Q6IPR3; 42734381
Isotype	IgG
Calculated MW	29794
Antigen Source	Homo sapiens
Target/Specificity	TYW3; TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.
Purification	TYW3 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	TYW3 antibody can be stored at 4 ℃, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody Form	Liquid
Application Notes	TYW3 antibody can be used for detection of TYW3 by Western blot at 1 µg/mL.
Positive Control	A549 Cell Lysate ;
Buffer	TYW3 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-ASC11335-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 9/4/2025

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