ATG14 Antibody

ATG14; At least three isoforms of ATG14 are known to exist; this antibody will detect all three isoforms

ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.

ATG14 {ECO:0000303|PubMed:18843052}

55309

ATG14 Antibody is affinity chromatography purified via peptide column.

ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 µg/mL. For immunofluorescence start at 20 µg/mL.

ATG14 Antibody is supplied in PBS containing 0.02% sodium azide.