LMX1A Antibody

Q8TE12

LMX1A Antibody: The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.

Polyclonal

LMX1A

Western blot analysis of MettL7B in human colon tissue lysate with MettL7B antibody at (A) 1 and (B) 2 µg/mL.

Western blot analysis of TLR9 in Jurkat cell lysate with TLR9 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide

NP_796372; 4009

42747

Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A.

The immunogen is located within amino acids 300 - 350 of LMX1A.

LMX1A antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

LMX1A antibody can be used for detection of LMX1A by Western blot at 1 - 2 μ g/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μ g/mL. For immunofluorescence start at 20 μ g/mL.

LMX1A Antibody is supplied in PBS containing 0.02% sodium azide.