« Back
Home /
GRINA Antibody

GRINA Antibody

Item no.	ABC-ASC11587
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	Q7Z429
Application	WB, E
Bio Background	GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
Bio References	Yamaji T, Nishikawa K and Hanada K et al. Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis. J. Biol. Chem. 2010; 285:35505-18. Nielsen JA, Chambers MA, Romm E, et al. Mouse transmembrane BAX inhibitor motif 3 (Tmbim3) encodes a 38 kDa transmembrane protein expressed in the central nervous system. Mol. Cell. Biochem. 2011; 357:73-81. Rojas-Rivera D, Armisén R, Colombo A, et al. TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ. 2012; 19:1013-26.
Clonality	Polyclonal
Gene ID	2907
Gene Name	GRINA
Reactivity	H
Legend image 1	Western blot analysis of GRINA in human testis tissue lysate with GRINA antibody at (A) 1 and (B) 2 µg/mL.
Type image 1	WB
Other Accession	NP_001009184; 57165375
Isotype	IgG
Calculated MW	41203
Antigen Source	homo sapiens
Target/Specificity	GRINA; GRINA antibody is predicted to not cross-react with other members of the TMBIM family.
Purification	GRINA Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	GRINA antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form	Liquid
Application Notes	GRINA antibody can be used for detection of GRINA by Western blot at 1 - 2 µg/mL.
Positive Control	Human Testis Tissue Lysate;
Buffer	GRINA Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-ASC11587-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 11/6/2025

Express Delivery: Save 22 days

Compare

Add to wishlist

Get an offer