Comparison

DHX36 Antibody

Item no. ABC-ASC11592
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Primary Accession
Q9H2U1
Application
WB, IHC-P, E
Bio Background
DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
Bio References
Cordin O, Banroques J, Tanner NK, et al. The DEAD-box protein family of RNA helicases. Gene 2006; 367:17-37.
Linder P. Dead-box proteins: a family affair—active and passive players in RNP-remodeling. Nucleic Acids Res. 2006; 34:4168-80.
Lattmann S, Giri B, Vaughn JP, et al. Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res. 2010; 38:6219-33.
Fu JJ, Li LY, Liu SF, et al. Expression research for human DDX36 and mouse Ddx36 gene in the adult testis. Yi Chuan Xue Bao 2003; 30: 201-208.
Clonality
Polyclonal
Gene ID
170506
Gene Name
DHX36 (HGNC:14410)
Reactivity
H, M
Legend image 1
Western blot analysis of DHX36 in mouse liver tissue lysate with DHX36 antibody at (A) 0.5 and (B) 1 µg/mL.
Type image 1
WB
Legend image 2
Immunohistochemistry of DHX36 in human liver tissue with DHX36 antibody at 5 µg/mL.
Type image 2
IHC
Other Accession
NP_065916; 167830433
Isotype
IgG
Calculated MW
114760
Antigen Source
homo sapiens
Target/Specificity
DHX36; At least four isoforms of DDX36 are known to exist; this antibody will detect the three longest isoforms.
Purification
DHX36 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
DHX36 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form
Liquid
Application Notes
DHX36 antibody can be used for detection of DHX36 by Western blot at 0.5 - 1 µg/mL.
Positive Control
Mouse Liver Tissue Lysate;
Buffer
DHX36 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close