Comparison

STAT3 Antibody

Item no. ABC-ASC11606
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, IF, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Citations Schaefer TS, Sanders LK, and Nathans D. Cooperative transcriptional activity of Jun and Stat3b, a short form of Stat3. Proc. Natl. Acad. Sci. USA 1995; 92:9097-101.
Leonard WJ and O'Shea JJ. Jaks and STATs: biological implications. Annu. Rev. Immunol. 1998; 16:293-322.
Schindler C and Darnell JE Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 1995; 64:621-51.
Rajan P. STATus and context within the mammalian nervous system. Mol. Med. 2011; 17:965-73
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Manufacturer - Applications
STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 µg/mL.
Manufacturer - Category
Primary Antibodies; Cancer; Cardiovascular; Developmental Biology; Microbiology; Signal Transduction; Stem Cells; Viral process; Host-virus interaction; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; JAK-STAT signaling; Jak-STAT signaling KEGG
Manufacturer - Targets
STAT3;
Storage Conditions
STAT3 antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background
STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system.
Clonality
Polyclonal
Gene Name
STAT3 {ECO:0000303|PubMed:9630560, ECO:0000312|HGNC:HGNC:11364}
Reactivity
H, M, Rat
Calculated Molecular Weight
88068
Antigen Source
homo sapiens
Purification
STAT3 Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
STAT3 antibody can be used for detection of STAT3 by Western blot at 1 - 2 µg/mL.
Positive Control
Human Small Intestine Tissue Lysate
Buffer
STAT3 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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