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GDPD5 Antibody

GDPD5 Antibody

Item no.	ABC-ASC11781
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, IF, ELISA, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Primary Accession	Q8WTR4
Application	WB, IHC-P, IF, E
Bio Background	The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2, 3). Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4).
Bio References	Nogusa Y, Fujioka Y, Komatsu R, et al. Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6. Gene 2004; 337:173-9. Rao M and Sockanathan S. Transmembrane protein GDE2 induces motor neuron differentiation in vivo. Science 2005; 309:2212-5. Yanaka N, Nogusa Y, Fujioka Y, et al. Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells. FEBS Lett. 2007; 581:712-8. Cao MD, Dopkens M, Krishnamachary B, et al. Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer. NMR Biomed. 2012; 25:1033-42.
Clonality	Polyclonal
Gene ID	81544
Gene Name	GDPD5 (HGNC:28804)
Reactivity	H, M, Rat
Legend image 1	Western blot analysis of GDPD5 in mouse kidney tissue lysate with GDPD5 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Type image 1	WB
Legend image 2	Immunohistochemistry of GDPD5 in human kidney tissue with GDPD5 antibody at 5 µg/mL.
Type image 2	IHC
Legend image 3	Immunofluorescence of GDPD5 in human kidney tissue with GDPD5 antibody at 20 µg/mL.
Type image 3	IF
Other Accession	NP_110419; 189571657
Isotype	IgG
Calculated MW	68586
Antigen Source	homo sapiens
Target/Specificity	GDPD5; GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.
Purification	GDPD5 antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage	GDPD5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form	Liquid
Application Notes	GDPD5 antibody can be used for detection of GDPD5 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry at 5 µg/mL. For Immunoflorescence start at 20 µg/mL.
Positive Control	Mouse Kidney;
Buffer	GDPD5 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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