Comparison

AJAP1 Antibody

Item no. ABC-ASC11919
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Primary Accession
Q9UKB5
Application
WB, E
Bio Background
The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1, 2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3, 4).
Bio References
Zeng L, Fee BE, Rivas MV, et al. Adherens junctional associated protein-1: a novel 1p36 tumor suppressor candidate in gliomas (Review). Int. J. Oncol. 2014; 45:13-7.
Han L, Zhang KL, Zhang JX, et al. AJAP1 is dysregulated at an early stage of gliomagenesis and suppresses invasion through cytoskeleton reorganization. CNS Neurosci. Ther. 2014; 20:429-37.
Gross JC, Schreiner A, Engels K, et al. E-cadherin surface levels in epithelial growth factor-stimulated cells depend on adherens junction protein shrew-1. Mol. Biol. Cell 2009; 20:3598-607.
Lin N, Di C, Bortoff K, et al. Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma. Mol. Cancer Res. 2012; 10:208-17.
Clonality
Polyclonal
Gene ID
55966
Gene Name
AJAP1
Reactivity
H, M, Rat
Legend image 1
Western blot analysis of AJAP1 in rat liver tissue lysate with AJAP1 antibody at 1 µg/ml.
Type image 1
WB
Other Accession
NP_061324; 9055278
Isotype
IgG
Calculated MW
44536
Antigen Source
homo sapiens
Target/Specificity
AJAP1; AJAP1 antibody is human, mouse and rat reactive.
Purification
AJAP1 antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
AJAP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form
Liquid
Application Notes
AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 - 2 µg/ml.
Positive Control
Rat Liver Tissue Lysate;
Buffer
AJAP1 antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

Delivery expected until 9/4/2025 

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