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AKT2 Antibody (monoclonal) (M03)

AKT2 Antibody (monoclonal) (M03)

Item no.	ABC-AT1101a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Metabolism Diabetes Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF
Clone	1D9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs.Lincova E, Hampl A, Pernicova Z, Star?ichova A, Kr?ma? P, Machala M, Kozubik A, Sou?ek K.Biochem Pharmacol. 2009 Sep 15;78(6):561-72. Epub 2009 May 9.
NCBI	NP_001617.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	RAC-beta serine/threonine-protein kinase,Protein kinase Akt-2,Protein kinase B beta,PKB beta,RAC-PK-beta,AKT2
Similar products	AKT2, RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, RAC-PK-beta, PKB beta
Available
Manufacturer - Targets	AKT2 (AAA58364, 100 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Clonality	Monoclonal
Gene Name	AKT2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant AKT2.
Reactivity	H, M, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	0.5 mg/ml
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAA58364
Gene Description	v-akt murine thymoma viral oncogene homolog 2
Gene Summary	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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