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ATF3 Antibody (monoclonal) (M04)

ATF3 Antibody (monoclonal) (M04)

Item no.	ABC-AT1223a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	8G5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG3 Kappa
Citations	1.Transcriptional regulators of the ?GNp63: Their role in limbal epithelial cell proliferation.Hsueh YJ, Kuo PC, Chen JK.J Cell Physiol. 2012 Jul 17. doi: 10.1002/jcp.24160.
NCBI	NP_001025458.1,NP_001035709.1,NP_001193413.2,NP_001193415.1,NP_001193417.2,NP_001665.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclic AMP-dependent transcription factor ATF-3,cAMP-dependent transcription factor ATF-3,Activating transcription factor 3,ATF3
Similar products	ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3, cAMP-dependent transcription factor ATF-3
Available
Manufacturer - Targets	ATF3 (AAH06322, 1 a.a. ~ 181 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Clonality	Monoclonal
Gene Name	ATF3 {ECO:0000303\|PubMed:7515060, ECO:0000312\|HGNC:HGNC:785}
Subtitle	Mouse monoclonal antibody raised against a full length recombinant ATF3.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH06322
Gene Description	activating transcription factor 3
Gene Summary	Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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