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BFSP1 Antibody (monoclonal) (M01)

BFSP1 Antibody (monoclonal) (M01)

Item no.	ABC-AT1292a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Clone	1B11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG
Citations	Autosomal recessive juvenile onset cataract associated with mutation in BFSP1. Ramachandran RD, et al. Hum Genet, 2007 May. PMID 17225135.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.The DNA sequence and comparative analysis of human chromosome 20. Deloukas P, et al. Nature, 2001 Dec 20-27. PMID 11780052.An autosomal dominant posterior polar cataract locus maps to human chromosome 20p12-q12. Yamada K, et al. Eur J Hum Genet, 2000 Jul. PMID 10909854.Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1. Rendtorff ND, et al. Genomics, 1998 Oct 1. PMID 9787085.
NCBI	NP_001155177.1,NP_001186.1,NP_001265535.1,NP_001265536.1,NP_001265537.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Filensin,Beaded filament structural protein 1,Lens fiber cell beaded-filament structural protein CP 115,CP115,Lens intermediate filament-like heavy,LIFL-H,BFSP1
Similar products	Filensin, BFSP1, Beaded filament structural protein 1, Lens fiber cell beaded-filament structural protein CP 115, CP115, Lens intermediate filament-like heavy, LIFL-H
Available
Manufacturer - Targets	BFSP1 (AAH41483, 1 a.a. ~ 540 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	BFSP1
Subtitle	Mouse monoclonal antibody raised against a full length recombinant BFSP1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000
Org Accession	AAH41483
Gene Description	beaded filament structural protein 1, filensin
Gene Summary	More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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