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CCL11 Antibody (monoclonal) (M01)

CCL11 Antibody (monoclonal) (M01)

Item no.	ABC-AT1413a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Neuroinflammation Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Clone	1C8-2C1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism. Beckers MM, et al. Eur J Intern Med, 2010 Aug. PMID 20603037.Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients. Wang Y, et al. Diabet Med, 2010 Apr. PMID 20536507.Eotaxins and CCR3 interaction regulates the Th2 environment of cutaneous T-cell lymphoma. Miyagaki T, et al. J Invest Dermatol, 2010 Sep. PMID 20505746.
NCBI	NP_002977.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Eotaxin,C-C motif chemokine 11,Eosinophil chemotactic protein,Small-inducible cytokine A11,CCL11,SCYA11
Similar products	Eotaxin, CCL11, SCYA11, Small-inducible cytokine A11, C-C motif chemokine 11, Eosinophil chemotactic protein
Available
Manufacturer - Targets	CCL11 (AAH17850, 24 a.a. ~ 97 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
Clonality	Monoclonal
Gene Name	CCL11
Subtitle	Mouse monoclonal antibody raised against a full length recombinant CCL11.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000
Org Accession	AAH17850
Gene Description	chemokine (C-C motif) ligand 11
Gene Summary	This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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