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CD40LG Antibody (monoclonal) (M01)

CD40LG Antibody (monoclonal) (M01)

Item no.	ABC-AT1439a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	200
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Anti-C1q antibodies, sCD40L, TWEAK and CD4/CD8 ratio in systemic lupus erythematosus and their relations to disease activity and renal involvement. ElGendi SS, et al. Egypt J Immunol, 2009. PMID 20726330.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-gene interaction between CD40 and CD40L reduces bone mineral density and increases osteoporosis risk in women. Pineda B, et al. Osteoporos Int, 2010 Jun 25. PMID 20577873.Augmented antibody response with premature germinal center regression in CD40L transgenic mice. Kishi Y, et al. J Immunol, 2010 Jul 1. PMID 20505144.Constitutive CD40L expression on B cells prematurely terminates germinal center response and leads to augmented plasma cell production in T cell areas. Bolduc A, et al. J Immunol, 2010 Jul 1. PMID 20505142.
NCBI	NP_000065.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD40 ligand,CD40-L,T-cell antigen Gp39,TNF-related activation protein,TRAP,Tumor necrosis factor ligand superfamily member 5,CD154,CD40 ligand,membrane form,CD40 ligand,soluble form,CD40LG,CD40L,TNFSF5,TRAP
Similar products	CD40LG, CD40L, soluble form, membrane form, TRAP, CD40-L, CD154, TNFSF5, TNF-related activation protein, T-cell antigen Gp39, Tumor necrosis factor ligand superfamily member 5, CD40 ligand
Available
Manufacturer - Targets	CD40LG (NP_000065, 101 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
Clonality	Monoclonal
Gene Name	CD40LG
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CD40LG.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_000065
Gene Description	CD40 ligand
Gene Summary	The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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