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CDC42BPB Antibody (monoclonal) (M03)

CDC42BPB Antibody (monoclonal) (M03)

Item no.	ABC-AT1465a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Antibodies By Cell Type Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Clone	2F4
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Overexpression and unique rearrangement of VH2 transcripts in immunoglobulin variable heavy chain genes in ankylosing spondylitis patients. Kim YJ, et al. Exp Mol Med, 2010 May 31. PMID 20177145.Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta. Choi SH, et al. J Biol Chem, 2008 Apr 18. PMID 18263588.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.
NCBI	NP_006026.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	CDC42-binding protein kinase beta, Serine/threonine-protein kinase MRCK beta, CDC42BP-beta, DMPK-like beta, MRCK beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, Myotonic dystrophy protein kinase-like beta, CDC42BPB {ECO:0000312\|EMBL:AAD375061}
Available
Manufacturer - Targets	CDC42BPB (AAD37506, 1580 a.a. ~ 1679 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.
Clonality	Monoclonal
Gene Name	CDC42BPB {ECO:0000312\|EMBL:AAD37506.1}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CDC42BPB.
Reactivity	H, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	AAD37506
Gene Description	CDC42 binding protein kinase beta (DMPK-like)
Gene Summary	This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq
Antigen Type	Recombinant Protein
Manufacturer - Alias	Serine/threonine-protein kinase MRCK beta, CDC42-binding protein kinase beta, CDC42BP-beta, DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, MRCK beta, Myotonic dystrophy protein kinase-like beta, CDC42BPB {ECO:0000312\|EMBL:AAD375061}
Manufacturer - Similar	Serine/threonine-protein kinase MRCK beta, CDC42-binding protein kinase beta, CDC42BP-beta, DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta, MRCK beta, Myotonic dystrophy protein kinase-like beta, CDC42BPB {ECO:0000312\|EMBL:AAD375061}

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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