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CFLAR Antibody (monoclonal) (M01)

CFLAR Antibody (monoclonal) (M01)

Item no.	ABC-AT1508a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, IF, IHC
Clone	2F12
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME-1, I-FLICE, MRIT, c-FLIP, CASP8 and FADD-like apoptosis regulator, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, Inhibitor of FLICE, MACH-related inducer of toxicity, Usurpin, CASP8 and FADD-like apoptosis regulator subunit p12, CASP8 and FADD-like apoptosis regulator subunit p43
Available
Primary Accession	O15519
Antigen Type	Recombinant Protein
Application	WB, IHC, IF
Bio References	Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL. Fricker N, et al. J Cell Biol, 2010 Aug 9. PMID 20696707.Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. Wang X, et al. PLoS One, 2010 Aug 3. PMID 20689807.Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Programmed cell death 4 (PDCD4) mediates the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by down-regulation of FLIP expression. Wang W, et al. Exp Cell Res, 2010 Sep 10. PMID 20595005.
Clonality	Monoclonal
Gene ID	8837
Gene Name	CFLAR
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CFLAR.
Reactivity	H
Legend image 1	Immunofluorescence of monoclonal antibody to CFLAR on HeLa cell. [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	CFLAR monoclonal antibody (M01), clone 2F12 Western Blot analysis of CFLAR expression in IMR-32 ( (Cat # AT1508a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	CFLAR monoclonal antibody (M01), clone 2F12. Western Blot analysis of CFLAR expression in K-562.
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	Western Blot analysis of CFLAR expression in transfected 293T cell line by CFLAR monoclonal antibody (M01), clone 2F12. Lane 1: CFLAR transfected lysate (Predicted MW: 55.3 KDa). Lane 2: Non-transfected lysate.
Type image 5	WB
Dilution image 5	1:500~1000
Legend image 6	Immunoperoxidase of monoclonal antibody to CFLAR on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
Type image 6	IHC
Legend image 7	Detection limit for recombinant GST tagged CFLAR is approximately 0.3ng/ml as a capture antibody.
Type image 7	E
Other Accession	BC001602
Isotype	IgG2a kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	CFLAR (AAH01602, 178 a.a. ~ 277 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001120655.1; NP_001120656.1; NP_001189444.1; NP_001189445.1; NP_001189446.1; NP_001189447.1; NP_001189448.1; NP_003870.4
	Clone: 2F12
Org Accession	AAH01602
Concentration	0.5 mg/ml
Gene Description	CASP8 and FADD-like apoptosis regulator

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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