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DDEF1 Antibody (monoclonal) (M01)

DDEF1 Antibody (monoclonal) (M01)

Item no.	ABC-AT1729a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, IF, ELISA
Clone	2G7
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ANK repeat and PH domain-containing protein 1, ASAP1, DDEF1, KIAA1249, Arf-GAP with SH3 domain, 130 kDa phosphatidylinositol 4, 5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, DEF-1, Differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP
Available
Primary Accession	Q9ULH1
Antigen Type	Recombinant Protein
Application	WB, IF, E
Bio References	ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients. M?ller T, et al. Oncogene, 2010 Apr 22. PMID 20154719.Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene). Nat Genet, 2009 Jul. PMID 19525955.Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes. Linkermann A, et al. Biochim Biophys Acta, 2009 Feb. PMID 19041431.Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1. Jian X, et al. J Biol Chem, 2009 Jan 16. PMID 19017632.Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome. Inoue H, et al. Mol Biol Cell, 2008 Oct. PMID 18685082.
Clonality	Monoclonal
Gene ID	50807
Gene Name	ASAP1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant DDEF1.
Reactivity	H, Rat
Legend image 1	Immunofluorescence of monoclonal antibody to DDEF1 on HeLa cell. [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	DDEF1 monoclonal antibody (M01), clone 2G7. Western Blot analysis of DDEF1 expression in PC-12 ( (Cat # AT1729a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	DDEF1 monoclonal antibody (M01), clone 2G7 Western Blot analysis of DDEF1 expression in IMR-32 ( (Cat # AT1729a )
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	Detection limit for recombinant GST tagged DDEF1 is approximately 0.03ng/ml as a capture antibody.
Type image 5	E
Other Accession	NM_018482
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	DDEF1 (NP_060952, 1030 a.a. ~ 1129 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001234925.1; NP_060952.2
	Clone: 2G7
Org Accession	NP_060952
Gene Description	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/6/2025

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