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EDN1 Antibody (monoclonal) (M01)

EDN1 Antibody (monoclonal) (M01)

Item no.	ABC-AT1850a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Immunoprecipitation Western Blot ELISA Cardiovascular Research Hypertension Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, ELISA
Clone	3D6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma.Marion A, Dieudonne FX, Patino-Garcia A, Lecanda F, Marie PJ, Modrowski D.Int J Cancer. 2012 Jun 1;130(11):2514-25. doi: 10.1002/ijc.26246. Epub 2011 Aug 16.2.Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice.Schildroth J, Rettig-Zimmermann J, Kalk P, Steege A, Fahling M, Sendeski M, Paliege A, Lai EY, Bachmann S, Persson PB, Hocher B, Patzak A.Nephrol Dial Transplant. 2010 Sep 2. [Epub ahead of print]3.Epithelial-to-Mesenchymal Transition and Resistance to Ingenol 3-Angelate, a Novel Protein Kinase C Modulator, in Colon Cancer Cells.Ghoul A, Serova M, Astorgues-Xerri L, Bieche I, Bousquet G, Varna M, Vidaud M, Phillips E, Weill S, Benhadji KA, Lokiec F, Cvitkovic E, Faivre S, Raymond E.Cancer Res. 2009 May 15;69(10):4260-9. Epub 2009 May 5.
NCBI	NP_001161791.1,NP_001946.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Endothelin-1,Preproendothelin-1,PPET1,Endothelin-1,ET-1,Big endothelin-1,EDN1
Similar products	Endothelin-1, EDN1, Preproendothelin-1, Big endothelin-1, ET-1, PPET1
Available
Manufacturer - Targets	EDN1 (AAH09720, 113 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	EDN1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant EDN1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IP WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH09720
Gene Description	endothelin 1
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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