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FAP Antibody (monoclonal) (M01)

FAP Antibody (monoclonal) (M01)

Item no.	ABC-AT1998a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Metabolism Glucose Homeostasis Antibodies By Cell Type Carcinoma Melanoma Sarcoma Immunoprecipitation Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, ELISA
Clone	100000
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation.Chung KM, Hsu SC, Chu YR, Lin MY, Jiaang WT, Chen RH, Chen XPLoS One. 2014 Feb 13;9(2):e88772. doi: 10.1371/journal.pone.0088772. eCollection 2014.2.Extracellular Hsp90 mediates an NF-κB dependent inflammatory stromal program: Implications for the prostate tumor microenvironment.Bohonowych J, Hance M, Nolan K, Defee M, Parsons C, Isaacs JProstate. 2013 Dec 16. doi: 10.1002/pros.22761.3.Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion.Denys H, Derycke L, Hendrix A, Westbroek W, Gheldof A, Narine K, Pauwels P, Gespach C, Bracke M, De Wever O.Cancer Lett. 2008 Aug 8;266(2):263-74.4.Fibroblast activation protein and chronic liver disease.Wang XM, Yao TW, Nadvi NA, Osborne B, McCaughan GW, Gorrell MD.Front Biosci. 2008 Jan 1;13:3168-80.
NCBI	NP_004451.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	soluble form, Seprase, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, SIMP, Prolyl endopeptidase FAP, Dipeptidyl peptidase FAP, FAPalpha, Serine integral membrane protease, Surface-expressed protease, APCE, 3421-, Antiplasmin-cleaving enzyme FAP, FAP (HGNC:3590)
Available
Manufacturer - Targets	FAP (AAH26250, 525 a.a. ~ 624 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.
Clonality	Monoclonal
Gene Name	FAP
Subtitle	Mouse monoclonal antibody raised against a partial recombinant FAP.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	0.5mg/ml
Dilution	IP WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH26250
Gene Description	fibroblast activation protein, alpha
Gene Summary	The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq
Antigen Type	Recombinant Protein
Manufacturer - Alias	Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, Fibroblast activation protein alpha, FAPalpha, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, 3421-, FAP ()
Manufacturer - Similar	Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, Fibroblast activation protein alpha, FAPalpha, Serine integral membrane protease, SIMP, Surface-expressed protease, Seprase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, 3421-, FAP (HGNC:3590)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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