Comparison

GALT Antibody (monoclonal) (M01)

Item no. ABC-AT2149a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IHC, ELISA
Clone 4C11
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations Molecular and biochemical characterization of the GALT gene in Korean patients with galactose-1-phosphate uridyltransferase deficiency. Ko DH, et al. Clin Chim Acta, 2010 Oct 9. PMID 20547145.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Classical galactosemia in Estonia: selective neonatal screening, incidence, and genotype/phenotype data of diagnosed patients. Ounap K, et al. J Inherit Metab Dis, 2010 Apr. PMID 20151200.Analysis of galactosemia-linked mutations of GALT enzyme using a computational biology approach. Facchiano A, et al. Protein Eng Des Sel, 2010 Feb. PMID 20008339.Galactose-1-phosphate uridyl transferase deficiency is not associated with M?llerian aplasia in Dutch patients. Nijland R, et al. J Pediatr Adolesc Gynecol, 2009 Aug. PMID 19646668.
NCBI NP_000146.2,NP_001245261.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Galactose-1-phosphate uridylyltransferase,Gal-1-P uridylyltransferase,UDP-glucose--hexose-1-phosphate uridylyltransferase,GALT
Similar products GALT, Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase
Available
Manufacturer - Targets
GALT (AAH15045, 1 a.a. ~ 379 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined.
Clonality
Monoclonal
Gene Name
GALT
Subtitle
Mouse monoclonal antibody raised against a full length recombinant GALT.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
IHC
E
Org Accession
AAH15045
Gene Description
galactose-1-phosphate uridylyltransferase
Gene Summary
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. [provided by RefSeq
Antigen Type
Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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