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GEM Antibody (monoclonal) (M01)

GEM Antibody (monoclonal) (M01)

Item no.	ABC-AT2188a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cytoskeleton Western Blot ELISA Primary Antibodies Immunostaining small GTPases Ras Subfamily RGK Subfamily
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	4B12
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	A systemic network for Chlamydia pneumoniae entry into human cells. Wang A, et al. J Bacteriol, 2010 Jun. PMID 20233927.An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904.Biochemical and structural characterization of the gem GTPase. Splingard A, et al. J Biol Chem, 2007 Jan 19. PMID 17107948.Structure-function studies of the G-domain from human gem, a novel small G-protein. Opatowsky Y, et al. FEBS Lett, 2006 Oct 30. PMID 17052716.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.
NCBI	NP_005252.1,NP_859053.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GTP-binding protein GEM,GTP-binding mitogen-induced T-cell protein,RAS-like protein KIR,GEM,KIR
Similar products	GEM, KIR, GTP-binding mitogen-induced T-cell protein, GTP-binding protein GEM, RAS-like protein KIR
Available
Manufacturer - Targets	GEM (AAH22010, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Clonality	Monoclonal
Gene Name	GEM
Subtitle	Mouse monoclonal antibody raised against a partial recombinant GEM.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 E
Org Accession	AAH22010
Gene Description	GTP binding protein overexpressed in skeletal muscle
Gene Summary	The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/4/2025

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