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HEY1 Antibody (monoclonal) (M07)

HEY1 Antibody (monoclonal) (M07)

Item no.	ABC-AT2357a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Antibodies By Cell Type ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	ELISA
Clone	4B3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	The Notch effector Hey1 associates with myogenic target genes to repress myogenesis. Buas MF, et al. J Biol Chem, 2010 Jan 8. PMID 19917614.HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions. Villaronga MA, et al. Oncogene, 2010 Jan 21. PMID 19802006.High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. Yerges LM, et al. J Bone Miner Res, 2009 Dec. PMID 19453261.Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway. Gould F, et al. J Virol, 2009 Jul. PMID 19369342.Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. Sharff KA, et al. J Biol Chem, 2009 Jan 2. PMID 18986983.
NCBI	NP_001035798.1,NP_036390.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	HEY1, CHF2, HERP2, HESR1, HRT-1, Hairy and enhancer of split-related protein 1, Hairy-related transcription factor 1, Cardiovascular helix-loop-helix factor 2, CHF-2, HES-related repressor protein 1, HRT1, Hairy/enhancer-of-split related with YRPW motif protein 1, BHLHB31, Class B basic helix-loop-helix protein 31, bHLHb31, HESR-1, hHRT1
Available
Manufacturer - Targets	HEY1 (NP_036390, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
Clonality	Monoclonal
Gene Name	HEY1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant HEY1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Org Accession	NP_036390
Gene Description	hairy/enhancer-of-split related with YRPW motif 1
Gene Summary	This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Antigen Type	Recombinant Protein
Manufacturer - Alias	Hairy/enhancer-of-split related with YRPW motif protein 1, Cardiovascular helix-loop-helix factor 2, CHF-2, Class B basic helix-loop-helix protein 31, bHLHb31, HES-related repressor protein 1, Hairy and enhancer of split-related protein 1, HESR-1, Hairy-related transcription factor 1, HRT-1, hHRT1, HEY1, BHLHB31, CHF2, HERP2, HESR1, HRT1
Manufacturer - Similar	Hairy/enhancer-of-split related with YRPW motif protein 1, Cardiovascular helix-loop-helix factor 2, CHF-2, Class B basic helix-loop-helix protein 31, bHLHb31, HES-related repressor protein 1, Hairy and enhancer of split-related protein 1, HESR-1, Hairy-related transcription factor 1, HRT-1, hHRT1, HEY1, BHLHB31, CHF2, HERP2, HESR1, HRT1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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