IL1A Antibody (monoclonal) (M01)

Item no.	ABC-AT2508a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	4B8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	CCL3 genotype and current depression increase risk of HIV-associated dementia. Levine AJ, et al. Neurobehav HIV Med, 2009 Nov. PMID 20725607.An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868.Interleukin-1A +4845(G>T) polymorphism is a factor predisposing to acne vulgaris. Szab? K, et al. Tissue Antigens, 2010 Jul 11. PMID 20630038.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
NCBI	NP_000566.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Interleukin-1 alpha,IL-1 alpha,Hematopoietin-1,IL1A,IL1F1
Similar products	IL-1 alpha, IL1A, Interleukin-1 alpha, Hematopoietin-1, IL1F1
Available
Manufacturer - Targets	IL1A (AAH13142, 172 a.a. ~ 271 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Clonality	Monoclonal
Gene Name	IL1A
Subtitle	Mouse monoclonal antibody raised against a partial recombinant IL1A.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH13142
Gene Description	interleukin 1, alpha
Gene Summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer' s disease. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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