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IRX3 Antibody (monoclonal) (M03)

IRX3 Antibody (monoclonal) (M03)

Item no.	ABC-AT2550a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, IF, ELISA
Clone	3D8
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IRX3, IRXB1, Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3
Available
Primary Accession	P78415
Antigen Type	Recombinant Protein
Application	WB, IF, E
Bio Background	IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).
Bio References	Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Ragvin A, et al. Proc Natl Acad Sci U S A, 2010 Jan 12. PMID 20080751.Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Trynka G, et al. Gut, 2009 Aug. PMID 19240061.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. Lewis MT, et al. Cell Tissue Res, 1999 Jun. PMID 10370142.
Clonality	Monoclonal
Gene ID	79191
Gene Name	IRX3
Subtitle	Mouse monoclonal antibody raised against a partial recombinant IRX3.
Reactivity	H
Legend image 1	Immunofluorescence of monoclonal antibody to IRX3 on HeLa cell. [antibody concentration 30 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.18 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	IRX3 monoclonal antibody (M03), clone 3D8. Western Blot analysis of IRX3 expression in Hela S3 NE ( (Cat # AT2550a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	IRX3 monoclonal antibody (M03), clone 3D8 Western Blot analysis of IRX3 expression in K-562 ( (Cat # AT2550a )
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	Detection limit for recombinant GST tagged IRX3 is approximately 0.03ng/ml as a capture antibody.
Type image 5	E
Other Accession	NM_024336
Isotype	IgG2a Kappa
Target/Specificity	IRX3 (NP_077312, 182 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_077312.2
	Clone: 3D8
Org Accession	NP_077312
Concentration	0.5 mg/ml
Gene Description	iroquois homeobox 3
Gene Summary	IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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