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ITPR1 Antibody (monoclonal) (M01)

ITPR1 Antibody (monoclonal) (M01)

Item no.	ABC-AT2575a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies ELISA Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	ELISA
Clone	2B6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.Microdomains of muscarinic acetylcholine and InsP3 receptors create InsP3 junctions and sites of Ca2+ wave initiation in smooth muscle.Olson ML, Sandison ME, Chalmers S, McCarron JG.J Cell Sci. 2012 Sep 3.
NCBI	NP_001093422.2,NP_002213.5
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Inositol 1,5-trisphosphate receptor type 1,IP3 receptor isoform 1,IP3R 1,InsP3R1,Type 1 inositol 1,5-trisphosphate receptor,Type 1 InsP3 receptor,ITPR1,INSP3R1
Similar products	Inositol 1, INSP3R1, ITPR1, Type 1 inositol 1, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, InsP3R1, IP3 receptor isoform 1, IP3R 1, Type 1 InsP3 receptor
Available
Manufacturer - Targets	ITPR1 (NP_002213, 2470 a.a. ~ 2577 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Clonality	Monoclonal
Gene Name	ITPR1 {ECO:0000303\|PubMed:7852357, ECO:0000312\|HGNC:HGNC:6180}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant ITPR1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Org Accession	NP_002213
Gene Description	inositol 1, 4, 5-triphosphate receptor, type 1
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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