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KRT18 Antibody (monoclonal) (M01)

KRT18 Antibody (monoclonal) (M01)

Item no.	ABC-AT2655a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies By Organ Bladder Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC
Clone	2F8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma. Yamashiro Y, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20659422. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations. Strnad P, et al. Gastroenterology, 2010 Sep. PMID 20538000. Significant high expression of cytokeratins 7, 8, 18, 19 in pulmonary large cell neuroendocrine carcinomas, compared to small cell lung carcinomas. Nagashio R, et al. Pathol Int, 2010 Feb. PMID 20398190. Relationship between serum concentrations of keratin-18 and apoptosis in chronic hepatitis C. Gonzalez-Quintela A, et al. Clin Chem Lab Med, 2010 Jun. PMID 20374042.
NCBI	NP_000215.1,NP_954657.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Keratin,type I cytoskeletal 18,Cell proliferation-inducing gene 46 protein,Cytokeratin-18,CK-18,Keratin-18,K18,KRT18,CYK18
Similar products	Keratin, KRT18, CK-18, type I cytoskeletal 18, CYK18, K18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, Keratin-18
Available
Manufacturer - Targets	KRT18 (AAH00180, 1 a.a. ~ 430 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Clonality	Monoclonal
Gene Name	KRT18
Subtitle	Mouse monoclonal antibody raised against a full length recombinant KRT18.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	0.5mg/ml
Dilution	IF IP WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAH00180
Gene Description	keratin 18
Gene Summary	KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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