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MAK Antibody (monoclonal) (M01)

MAK Antibody (monoclonal) (M01)

Item no.	ABC-AT2767a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applications	WB, IF
Clone	300000
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAK, Serine/threonine-protein kinase MAK, Male germ cell-associated kinase
Available
Primary Accession	P20794
Antigen Type	Recombinant Protein
Application	WB, IF
Bio Background	The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
Bio References	Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Fu Z, et al. Mol Cell Biol, 2006 Nov. PMID 16954377.Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. Ma AH, et al. Cancer Res, 2006 Sep 1. PMID 16951154.Complete sequencing and characterization of 21, 243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.The DNA sequence and analysis of human chromosome 6. Mungall AJ, et al. Nature, 2003 Oct 23. PMID 14574404.Generation and initial analysis of more than 15, 000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Clonality	Monoclonal
Gene ID	4117
Gene Name	MAK
Subtitle	Mouse monoclonal antibody raised against a partial recombinant MAK.
Reactivity	H, M, Rat
Legend image 1	Immunofluorescence of monoclonal antibody to MAK on HepG2 cell. [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.41 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	MAK monoclonal antibody (M01), clone 3E5. Western Blot analysis of MAK expression in PC-12((Cat # AT2767a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	MAK monoclonal antibody (M01), clone 3E5 Western Blot analysis of MAK expression in HepG2 ( (Cat # AT2767a )
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	MAK monoclonal antibody (M01), clone 3E5. Western Blot analysis of MAK expression in Raw 264.7((Cat # AT2767a )
Type image 5	WB
Dilution image 5	1:500~1000
Legend image 6	MAK monoclonal antibody (M01), clone 3E5. Western Blot analysis of MAK expression in NIH/3T3((Cat # AT2767a )
Type image 6	WB
Dilution image 6	1:500~1000
Other Accession	BC039825
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	MAK (AAH39825, 358 a.a. ~ 457 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001229314.1; NP_001229886.1; NP_005897.1
	Clone: 300000
Org Accession	AAH39825
Gene Description	male germ cell-associated kinase
Gene Summary	The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. [provided by RefSeq

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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