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NBR1 Antibody (monoclonal) (M05)

NBR1 Antibody (monoclonal) (M05)

Item no.	ABC-AT2978a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cell Status Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	5C3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. Mardakheh FK, et al. J Cell Biol, 2009 Oct 19. PMID 19822672.Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover. Waters S, et al. FEBS Lett, 2009 Jun 18. PMID 19427866.NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets. Kirkin V, et al. Autophagy, 2009 Jul. PMID 19398892.A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Kirkin V, et al. Mol Cell, 2009 Feb 27. PMID 19250911.
NCBI	NP_005890.2,NP_114064.1,NP_114068.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Next to BRCA1 gene 1 protein,Cell migration-inducing gene 19 protein,Membrane component chromosome 17 surface marker 2,Neighbor of BRCA1 gene 1 protein,Protein 1A1-3B,NBR1,1A13B,KIAA0049,M17S2
Similar products	NBR1, KIAA0049, M17S2, Next to BRCA1 gene 1 protein, 1A13B, Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B
Available
Manufacturer - Targets	NBR1 (NP_005890, 2 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.
Clonality	Monoclonal
Gene Name	NBR1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant NBR1.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1 mg/ml
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_005890
Gene Description	neighbor of BRCA1 gene 1
Gene Summary	The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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