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PBK Antibody (monoclonal) (M07)

PBK Antibody (monoclonal) (M07)

Item no.	ABC-AT3197a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Neural Development Antibodies By Cell Type Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Progenitor Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC
Clone	3A7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.PBK/TOPK in the differential diagnosis of cholangiocarcinoma from hepatocellular carcinoma and its involvement in prognosis of human cholangiocarcinoma. He F, et al. Hum Pathol, 2010 Mar. PMID 19954816.Critical roles of T-LAK cell-originated protein kinase in cytokinesis. Park JH, et al. Cancer Sci, 2010 Feb. PMID 19900192.Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Uhl GR, et al. Arch Gen Psychiatry, 2008 Jun. PMID 18519826.Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells. Zhu F, et al. Gastroenterology, 2007 Jul. PMID 17631144.
NCBI	NP_001265874.1,NP_060962.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Lymphokine-activated killer T-cell-originated protein kinase,Cancer/testis antigen 84,CT84,MAPKK-like protein kinase,Nori-3,PDZ-binding kinase,Spermatogenesis-related protein kinase,SPK,T-LAK cell-originated protein kinase,PBK,TOPK
Similar products	SPK, PBK, Lymphokine-activated killer T-cell-originated protein kinase, PDZ-binding kinase, T-LAK cell-originated protein kinase, CT84, Nori-3, TOPK, MAPKK-like protein kinase, Cancer/testis antigen 84, Spermatogenesis-related protein kinase
Available
Manufacturer - Targets	PBK (AAH15191, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
Clonality	Monoclonal
Gene Name	PBK
Subtitle	Mouse monoclonal antibody raised against a partial recombinant PBK.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAH15191
Gene Description	PDZ binding kinase
Gene Summary	This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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