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PLA2G1B Antibody (monoclonal) (M01)

PLA2G1B Antibody (monoclonal) (M01)

Item no.	ABC-AT3328a
Manufacturer	Abcepta
Amount	100 ug
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot ELISA Enzymes Fatty Acid Catabolism Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	1B3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Structural insight into the activation mechanism of human pancreatic prophospholipase A2. Xu W, et al. J Biol Chem, 2009 Jun 12. PMID 19297324.Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta. Han C, et al. J Cell Biochem, 2008 Oct 1. PMID 18636547.The effects of beta2 adrenergic receptor gene polymorphism in lipid profiles. Kao WT, et al. Lipids Health Dis, 2008 May 21. PMID 18492292.
NCBI	NP_000919.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Phospholipase A2,Group IB phospholipase A2,Phosphatidylcholine 2-acylhydrolase 1B,PLA2G1B,PLA2,PLA2A,PPLA2
Similar products	PLA2G1B, PLA2, PLA2A, PPLA2, Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B
Available
Manufacturer - Targets	PLA2G1B (AAH05386, 17 a.a. ~ 70 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .
Clonality	Monoclonal
Gene Name	PLA2G1B
Subtitle	Mouse monoclonal antibody raised against a full length recombinant PLA2G1B.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 E
Org Accession	AAH05386
Gene Description	phospholipase A2, group IB (pancreas)
Gene Summary	Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]).[supplied by OMIM
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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